Purine nucleosides
Medchemexpress LLC Deoxyguanosine triphosphate trisodium solution | 93919-41-6 | 99.95% | 573.13 | 57.31 MG
Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. It is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
- Nucleotide precursor for DNA synthesis.
- Used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
- High purity: 99.95%.
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 5mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Cambridge Isotope Laboratories 2-Deoxyadenosine monohydrate (13C10 98% 15N5 96-98%) 25 mg
2-Deoxyadenosine monohydrate (13C10 98% 15N5 96-98%) 25 mg
Apexbio Technology LLC 2'-Deoxyguanosine 961-07-9 5g
2 -Deoxyguanosine (CAS 961-07-9) is a purine deoxyribonucleoside comprising guanine coupled to a deoxyribose moiety As an essential constituent of DNA it serves as a substrate in multiple nucleotide metabolism pathways Its interconversion with 2 -deoxyguanosine 5 -monophosphate is mediated by purine 5 -nucleotidase and deoxyguanosine kinase reflecting its role in nucleic acid turnover In biomedical research 2 -deoxyguanosine is utilized to study DNA synthesis repair mechanisms and enzymatic processes involving nucleoside metabolism Altered deoxyguanosine homeostasis has been implicated in purine nucleoside phosphorylase deficiency underscoring its significance in inherited metabolic disorders
Apexbio Technology LLC 2'-Deoxyguanosine 961-07-9 1g
2 -Deoxyguanosine (CAS 961-07-9) is a purine deoxyribonucleoside comprising guanine coupled to a deoxyribose moiety As an essential constituent of DNA it serves as a substrate in multiple nucleotide metabolism pathways Its interconversion with 2 -deoxyguanosine 5 -monophosphate is mediated by purine 5 -nucleotidase and deoxyguanosine kinase reflecting its role in nucleic acid turnover In biomedical research 2 -deoxyguanosine is utilized to study DNA synthesis repair mechanisms and enzymatic processes involving nucleoside metabolism Altered deoxyguanosine homeostasis has been implicated in purine nucleoside phosphorylase deficiency underscoring its significance in inherited metabolic disorders
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 100.0% | 267.25 | 25 MG
2'-Deoxyguanosine is a purine nucleoside with various biological activities. It can induce DNA division in mouse thymus cells and acts as a potent cell division inhibitor in plant cells. It also demonstrates antiproliferative and antiviral effects against several cell lines and viruses.
- Induces DNA division in mouse thymus cells.
- Acts as a potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells.
- Exhibits antiviral activity against varicella zoster virus (VZV) Oka strain.
- Exhibits antiviral activity against human cytomegalovirus (HCMV) AD 169 strain.
- Exhibits antiviral activity against herpes simplex virus-1 VR-3 strain.
- Exhibits antiviral activity against herpes simplex virus-2 (HSV-2) Ms strain.
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 50 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. It causes rapid cell death for the majority of cancer cell lines tested with IC50s between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreases tumor growth rate and increases telomere dysfunction in tumor cells in vivo.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Results in rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo
Medchemexpress LLC 5'-Deoxyadenosine | 4754-39-6 | 99.9% | 251.24 | 10 MG
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. It demonstrates anti-orthopoxvirus activity.
- Oxidized nucleoside
- Found in the urine of normal subjects
- Shows anti-orthopoxvirus activity
- For research use only
![eMolecules 892-48-8 | 5'-CHLORO-5'-DEOXYADENOSINE | AstaTech | MFCD00049038 | 285.690 | C10H12ClN5O3 | 95.000 | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O | 25g | 308519687](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000164417.jpg-250.jpg)
eMolecules 892-48-8 | 5'-CHLORO-5'-DEOXYADENOSINE | AstaTech | MFCD00049038 | 285.690 | C10H12ClN5O3 | 95.000 | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O | 25g | 308519687
5'-CHLORO-5'-DEOXYADENOSINE | AstaTech | 892-48-8 | MFCD00049038 | 285.690 | C10H12ClN5O3 | 95.000 | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O | 25g | 308519687
Medchemexpress LLC N6,N6-dimethyladenosine | 2620-62-4 | MFCD00022822 | 100.0% | 295.29 g·mol⁻1 | C12H17N5O4 | 1 ML
N6,N6-dimethyladenosine is a modified ribonucleoside used as an analytical standard and research reagent. It is supplied as solid material or as a 10 mM solution in DMSO and is used in studies of RNA modification, cellular signaling (including AKT pathway modulation), and viral entry protein interactions.
- High purity (>99.9%) suitable for analytical use.
- Available as solid and 10 mM solution in DMSO for convenient handling.
- Molecular formula C12H17N5O4 and molecular weight 295.29 g·mol⁻1.
- Suitable for studies of RNA modification and cellular signaling.
- Certificate of analysis and safety data sheet available.
Apexbio Technology LLC 2-Deoxyadenosine 958-09-8 500mg
2-Deoxyadenosine (CAS 958-09-8) is a synthetic purine nucleoside analog that functions as a demethylated nucleoside in biological systems Structurally similar to adenosine but lacking a hydroxyl group at the 2 position it selectively pairs with deoxythymidine during DNA synthesis 2-Deoxyadenosine influences regulatory pathways associated with DNA replication and repair serving as a molecular probe to study these processes It is extensively utilized in molecular biology and genomics for investigating DNA synthesis repair mechanisms and the dynamics of nucleic acid metabolism
Medchemexpress LLC 2'-Deoxyguanosine-13C10,15N5 | 872624-05-0 | 282.13 | 1 MG
2'-Deoxyguanosine-13C10,15N5 is a 13C- and 15N-labeled 2'-Deoxyguanosine for research use only. This compound is used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process, with deuteration showing potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
TARGETMOL CHEMICALS INC 2 5 -Dideoxyadenosine 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor, binding to the P-site with an IC50 of 3 uM. Purity 99.55%